Research Publications

Scientific journals on Maastricht whole body indirect calorimetry

Whole body indirect calorimetry is an invaluable, powerful tool in the field of human metabolism. The reliable and validated system from Maastricht Instruments BV has been widely used in international research studies for numerous applications, from fundamental energy expenditure to type II diabetes, environmental (e.g. temperature) influences and nutrition studies.

List of research publications (sorted by year):

Te Kulve M, Schlangen L, Schellen L, Souman JL, van Marken Lichtenbelt W.
Correlated colour temperature of morning light influences alertness and body temperature.
Physiol Behav. 2018 Mar 1;185:1-13. doi: 10.1016/j.physbeh.2017.12.004. Epub 2017 Dec 6.
PMID:29223712

 

Sun L, Camps SG, Goh HJ, Govindharajulu P, Schaefferkoetter JD, Townsend DW, Verma SK, Velan SS, Sun L, Sze SK, Lim SC, Boehm BO, Henry CJ, Leow MK.
Capsinoids activate brown adipose tissue (BAT) with increased energy expenditure associated with subthreshold 18-fluorine fluorodeoxyglucose uptake in BAT-positive humans confirmed by positron emission tomography scan.
Am J Clin Nutr. 2018 Jan 1;107(1):62-70. doi: 10.1093/ajcn/nqx025.
PMID:29381803

 

Schoffelen PFM, Plasqui G
Classical experiments in whole-body metabolism: open-circuit respirometry-diluted flow chamber, hood, or facemask systems
Eur J Appl Physiol. 2018 Jan;118(1):33-49. doi: 10.1007/s00421-017-3735-5. Epub 2017 Oct 27. Review.
PMID: 29080000

 

Camps SG, Kaur B, Quek RYC, Henry CJ
Does the ingestion of a 24 hour low glycaemic index Asian mixed meal diet improve glycaemic response and promote fat oxidation? A controlled, randomized cross-over study
Nutr J. 2017 Jul 12;16(1):43. doi: 10.1186/s12937-017-0258-1.
PMID: 28701162

 

Te Kulve M, Schlangen LJM, Schellen L, Frijns AJH, van Marken Lichtenbelt WD.
The impact of morning light intensity and environmental temperature on body temperatures and alertness.
Physiol Behav. 2017 Jun 1;175:72-81. doi: 10.1016/j.physbeh.2017.03.043. Epub 2017 Mar 30.
PMID:28366816

 

Henry CJ, Kaur B, Quek RYC, Camps SG
A Low Glycaemic Index Diet Incorporating Isomaltulose Is Associated with Lower Glycaemic Response and Variability, and Promotes Fat Oxidation in Asians
Nutrients. 2017 May 9;9(5). pii: E473. doi: 10.3390/nu9050473.
PMID: 28486426

 

Valenti G, Bonomi AG, Westerterp KR.
Quality Sleep Is Associated With Overnight Metabolic Rate in Healthy Older Adults.
J Gerontol A Biol Sci Med Sci. 2017 Apr 1;72(4):567-571. doi: 10.1093/gerona/glw107.
PMID:27260527

 

Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, Schlein C, Piepenburg J, Boon MR, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson SK, Fischer M, Wijers SL, van Marken Lichtenbelt W, Scheja L, Rensen PCN, Heeren J.
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport.
Nat Commun. 2017 Apr 19;8:15010. doi: 10.1038/ncomms15010.
PMID:28422089 | PMCID:PMC5399294

 

Pallubinsky H, Schellen L, Kingma BRM, Dautzenberg B, van Baak MA, van Marken Lichtenbelt WD.
Thermophysiological adaptations to passive mild heat acclimation.
Temperature (Austin). 2017 Mar 10;4(2):176-186. doi: 10.1080/23328940.2017.1303562. eCollection 2017.
PMID:28680933 | PMCID:PMC5489020

 

Goh HJ, Govindharajulu P, Camps SG, Tan SY, Henry CJ
Gross and relative energy cost of domestic household activities in Asian men
Eur J Clin Nutr. 2016 Dec;70(12):1414-1419. doi: 10.1038/ejcn.2016.134. Epub 2016 Jul 27.
PMID: 2746026

 

Schrauwen P, van Marken Lichtenbelt WD.
Combatting type 2 diabetes by turning up the heat.
Diabetologia. 2016 Nov;59(11):2269-2279. doi: 10.1007/s00125-016-4068-3. Epub 2016 Sep 3. Review.
PMID:27591854 | PMCID:PMC5506100

 

van Moorsel D, Hansen J, Havekes B, Scheer FA, Jörgensen JA, Hoeks J, Schrauwen-Hinderling VB, Duez H, Lefebvre P, Schaper NC, Hesselink MK, Staels B, Schrauwen P.
Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity.
Mol Metab. 2016 Jul 1;5(8):635-45. doi: 10.1016/j.molmet.2016.06.012. eCollection 2016 Aug.
PMID:27656401 | PMCID:PMC5021670

 

Hanssen MJ, van der Lans AA, Brans B, Hoeks J, Jardon KM, Schaart G, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD.
Short-term Cold Acclimation Recruits Brown Adipose Tissue in Obese Humans.
Diabetes. 2016 May;65(5):1179-89. doi: 10.2337/db15-1372. Epub 2015 Dec 30.
PMID:26718499

 

Chen Y, Buyel JJ, Hanssen MJ, Siegel F, Pan R, Naumann J, Schell M, van der Lans A, Schlein C, Froehlich H, Heeren J, Virtanen KA, van Marken Lichtenbelt W, Pfeifer A.
Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity.
Nat Commun. 2016 Apr 27;7:11420. doi: 10.1038/ncomms11420.
PMID:27117818 | PMCID:PMC4853423

 

Kaur B, Quek Yu Chin R, Camps S, Henry CJ
The impact of a low glycaemic index (GI) diet on simultaneous measurements of blood glucose and fat oxidation: A whole body calorimetric study
J Clin Transl Endocrinol. 2016 Apr 26;4:45-52. doi: 10.1016/j.jcte.2016.04.003. eCollection 2016 Jun.
PMID: 29159130

 

Daanen HA, Van Marken Lichtenbelt WD.
Human whole body cold adaptation.
Temperature (Austin). 2016 Feb 22;3(1):104-18. doi: 10.1080/23328940.2015.1135688. eCollection 2016 Jan-Mar. Review.
PMID:27227100 | PMCID:PMC4861193

 

te Kulve M, Schellen L, Schlangen LJ, van Marken Lichtenbelt WD.
The influence of light on thermal responses.
Acta Physiol (Oxf). 2016 Feb;216(2):163-85. doi: 10.1111/apha.12552. Epub 2015 Aug 6. Review.
PMID:26172218

 

van der Lans AA, Vosselman MJ, Hanssen MJ, Brans B, van Marken Lichtenbelt WD.
Supraclavicular skin temperature and BAT activity in lean healthy adults.
J Physiol Sci. 2016 Jan;66(1):77-83. doi: 10.1007/s12576-015-0398-z. Epub 2015 Sep 29.
PMID:26420686 | PMCID:PMC4676963

 

Dijk W, Heine M, Vergnes L, Boon MR, Schaart G, Hesselink MK, Reue K, van Marken Lichtenbelt WD, Olivecrona G, Rensen PC, Heeren J, Kersten S.
ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure.
Elife. 2015 Oct 17;4. pii: e08428. doi: 10.7554/eLife.08428.
PMID:26476336 | PMCID:PMC4709329

 

Boon MR, van Marken Lichtenbelt WD.
Brown Adipose Tissue: A Human Perspective.
Handb Exp Pharmacol. 2016;233:301-19. doi: 10.1007/164_2015_11. Review.
PMID:26003832

 

Broeders EP, Nascimento EB, Havekes B, Brans B, Roumans KH, Tailleux A, Schaart G, Kouach M, Charton J, Deprez B, Bouvy ND, Mottaghy F, Staels B, van Marken Lichtenbelt WD, Schrauwen P.
The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity.
Cell Metab. 2015 Sep 1;22(3):418-26. doi: 10.1016/j.cmet.2015.07.002. Epub 2015 Jul 30.
PMID:26235421

 

Amor JD, Hattersley JG, Barber TM, James CJ
Characterization of wrist-wearable activity measurement using whole body calorimetry in semi-free living conditions
Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:3735-8. doi: 10.1109/EMBC.2015.7319205.
PMID: 26737105

 

Hanssen MJ, Hoeks J, Brans B, van der Lans AA, Schaart G, van den Driessche JJ, Jörgensen JA, Boekschoten MV, Hesselink MK, Havekes B, Kersten S, Mottaghy FM, van Marken Lichtenbelt WD, Schrauwen P.
Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus.
Nat Med. 2015 Aug;21(8):863-5. doi: 10.1038/nm.3891. Epub 2015 Jul 6.
PMID:26147760

 

Schrauwen P, van Marken Lichtenbelt WD, Spiegelman BM.
The future of brown adipose tissues in the treatment of type 2 diabetes.
Diabetologia. 2015 Aug;58(8):1704-7. doi: 10.1007/s00125-015-3611-y. Epub 2015 May 9.
PMID:25957230

 

van der Lans AA, Boon MR, Haks MC, Quinten E, Schaart G, Ottenhoff TH, van Marken Lichtenbelt WD.
Cold acclimation affects immune composition in skeletal muscle of healthy lean subjects.
Physiol Rep. 2015 Jul;3(7). pii: e12394. doi: 10.14814/phy2.12394.
PMID:26149277 | PMCID:PMC4552515

 

Reddy NL, Peng C, Carreira MC, Halder L, Hattersley J, Piya MK, Tripathi G, Randeva HS, Casanueva FF, McTernan PG, Kumar S, Barber TM
Enhanced thermic effect of food, postprandial NEFA suppression and raised adiponectin in obese women who eat slowly
Clin Endocrinol (Oxf). 2015 Jun;82(6):831-7.doi:10.1111/cen.12652. Epub 2015 Jan 9.
PMID: 25369176

 

Robinson SL, Hattersley J, Frost GS, Chambers ES, Wallis GA
Maximal fat oxidation during exercise is positively associated with 24-hour fat oxidation and insulin sensitivity in young, healthy men
J Appl Physiol (1985). 2015 Jun 1;118(11):1415-22. doi: 10.1152/japplphysiol.00058.2015. Epub 2015 Mar 26.
PMID: 25814634

 

Bucerius J, Vijgen GH, Brans B, Bouvy ND, Bauwens M, Rudd JH, Havekes B, Fayad ZA, van Marken Lichtenbelt WD, Mottaghy FM.
Impact of bariatric surgery on carotid artery inflammation and the metabolic activity in different adipose tissues.
Medicine (Baltimore). 2015 May;94(20):e725. doi: 10.1097/MD.0000000000000725.
PMID:25997038 | PMCID:PMC4602867

 

Horowitz M, Kenny GP, McAllen RM, van Marken Lichtenbelt WD.
Thermal physiology in a changing thermal world.
Temperature (Austin). 2015 Apr 14;2(1):22-6. doi: 10.1080/23328940.2015.1017088. eCollection 2015 Jan-Mar.
PMID:27226998 | PMCID:PMC4843882

 

van der Lans AA, Wierts R, Vosselman MJ, Schrauwen P, Brans B, van Marken Lichtenbelt WD.
Cold-activated brown adipose tissue in human adults: methodological issues.
Am J Physiol Regul Integr Comp Physiol. 2014 Jul 15;307(2):R103-13. Review.
PMID:24871967

 

Vosselman MJ, Vijgen GH, Kingma BR, Brans B, van Marken Lichtenbelt WD.
Frequent extreme cold exposure and brown fat and cold-induced thermogenesis: a study in a monozygotic twin.
PLoS One. 2014 Jul 11;9(7):e101653. doi: 10.1371/journal.pone.0101653. eCollection 2014.
PMID:25014028 | PMCID:PMC4094425

 

Janssens PL, Hursel R, Westerterp-Plantenga MS
Capsaicin increases sensation of fullness in energy balance, and decreases desire to eat after dinner in negative energy balance
Appetite. 2014 Jun;77:44-9. doi:10.1016/j.appet.2014.02.018. Epub 2014 Mar 12.
PMID: 2463093

 

van Can J, Sloth B, Jensen CB, Flint A, Blaak EE, Saris WH
Effects of the once-daily GLP-1 analog liraglutide on gastric emptying, glycemic parameters, appetite and energy metabolism in obese, non-diabetic adults
Int J Obes (Lond). 2014 Jun;38(6):784-93. doi: 10.1038/ijo.2013.162. Epub 2013 Sep 3.
PMID: 23999198 | PMCID: PMC4052428

 

Jacquot CM, Schellen L, Kingma BR, van Baak MA, van Marken Lichtenbelt WD.
Influence of thermophysiology on thermal behavior: the essentials of categorization.
Physiol Behav. 2014 Apr 10;128:180-7. doi: 10.1016/j.physbeh.2014.01.025. Epub 2014 Feb 8.
PMID:24518871

 

Konings E, Schoffelen PF, Stegen J, Blaak EE
Effect of polydextrose and soluble maize fibre on energy metabolism, metabolic profile and appetite control in overweight men and women
Br J Nutr. 2014 Jan 14;111(1):111-21. doi:10.1017/S0007114513002183. Epub 2013 Jul 23.
PMID: 23880340

 

Munsters MJ, Geraedts MC, Saris WH
Effects of different protein an d glycemic index diets on metabolic profiles and substrate partitioning in lean healthy males
Appl Physiol Nutr Metab. 2013 Nov;38(11):1107-14. doi:10.1139/apnm-2012-0409. Epub 2013 Apr 25.
PMID: 24053517

 

Gonnissen HK, Drummen M, Rosique Esteban N, Schoffelen PF, Westerterp-Plantenga MS
Overnight energy expenditure determined by whole-body indirect calorimetry does not differ during different sleep stages
Am J Clin Nutr. 2013 Oct;98(4):867-71. doi:10.3945/ajcn.113.067884. Epub 2013 Jul 31.
PMID: 23902787

 

Vijgen GH, Bouvy ND, Leenen L, Rijkers K, Cornips E, Majoie M, Brans B, van Marken Lichtenbelt WD.
Vagus nerve stimulation increases energy expenditure: relation to brown adipose tissue activity.
PLoS One. 2013 Oct 23;8(10):e77221. doi: 10.1371/journal.pone.0077221. eCollection 2013.
PMID:24194874 | PMCID:PMC3806746

 

van der Lans AA, Hoeks J, Brans B, Vijgen GH, Visser MG, Vosselman MJ, Hansen J, Jörgensen JA, Wu J, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD.
Cold acclimation recruits human brown fat and increases nonshivering thermogenesis.
J Clin Invest. 2013 Aug;123(8):3395-403. doi: 10.1172/JCI68993. Epub 2013 Jul 15.
PMID:23867626 | PMCID:PMC3726172

 

Hursel R, Gonnissen HK, Rutters F, Martens EA, Westerterp-Plantenga MS
Disadvantageous shift in energy balance is primarily expressed in high-quality sleepers after a decline in quality sleep because of disturbance
Am J Clin Nutr. 2013 Aug;98(2):367-73. doi:10.3945/ajcn.112.054924. Epub 2013 Jun 26.
PMID: 23803894

 

Gonnissen HK, Mazuy C, Rutters F, Martens EA, Adam TC, Westerterp-Plantenga MS
Sleep architecture when sleeping at an unusual circadian time and associations with insulin sensitivity
PLoS One. 2013 Aug 8;8(8):e72877. doi:10.1371/journal.pone.0072877. eCollection 2013.
PMID: 23951335 | PMCID: PMC3738551

 

Janssens PL, Hursel R, Martens EA, Westerterp-Plantenga MS
Acute effects of capsaicin on energy expenditure and fat oxidation in negative energy balance
PLoS One. 2013 Jul 2;8(7):e67786. doi:10.1371/journal.pone.0067786. Print 2013.
PMID: 23844093 | PMCID:PMC3699483

 

Virtanen KA, van Marken Lichtenbelt WD, Nuutila P.
Brown adipose tissue functions in humans.
Biochim Biophys Acta. 2013 May;1831(5):1004-8. doi: 10.1016/j.bbalip.2012.12.011. Epub 2012 Dec 26.
PMID:23274235

 

van Herpen NA, Sell H, Eckel J, Schrauwen P, Mensink RP
Prolonged fasting and the effects on biomarkers of inflammation and on adipokines in healthy lean men
Horm Metab Res. 2013 May;45(5):378-82. doi: 10.1055/s-0032-1330015. Epub 2012 Dec 12.
PMID: 23235922

 

Smeets AJ, Janssens PL, Westerterp-Plantenga MS
Addition of capsaicin and exchange of carbohydrate with protein counteract energy intake restriction effects on fullness and energy expenditure
J Nutr. 2013 Apr;143(4):442-7. doi:10.3945/jn.112.170613. Epub 2013 Feb 13.
PMID: 23406619

 

Gonnissen HK, Rutters F, Mazuy C, Martens EA, Adam TC, Westerterp-Plantenga MS
Effect of a phase advance and phase delay of the 24-h cycle on energy metabolism, appetite, and related hormones
Am J Clin Nutr. 2012 Oct;96(4):689-97. Epub 2012 Aug 22.
PMID: 22914550

 

Rutters F, Gonnissen HK, Hursel R, Lemmens SG, Martens EA, Westerterp-Plantenga MS
Distinct associations between energy balance and the sleep characteristics slow wave sleep and rapid eye movement sleep
Int J Obes (Lond). 2012 Oct;36(10):1346-52. doi: 10.1038/ijo.2011.250. Epub 2012 Jan 10.
PMID: 22234280

 

Wulan SN, Westerterp KR, Plasqui G
Dietary and 24-h fat oxidation in Asians and whites who differ in body composition.
Am J Clin Nutr. 2012 Jun;95(6):1335-41. doi: 10.3945/ajcn.111.031369. Epub 2012 May 2.
PMID:22552026

 

Munsters MJ, Saris WH
Effects of meal frequency on metabolic profiles and substrate partitioning in lean healthy males
PLoS One. 2012;7(6):e38632. doi: 10.1371/journal.pone.0038632. Epub 2012 Jun 13.
PMID: 22719910 | PMCID: PMC3374835

 

Baadjou VA, van Eijsden-Besseling MD, Samama-Polak AL, Smeets RJ, Passos VL, Westerterp KR
Energy expenditure in brass and woodwind instrumentalists: the effect of body posture
Med Probl Perform Art. 2011 Dec;26(4):218-23.
PMID: 22211199

 

Hursel R, Rutters F, Gonnissen HK, Martens EA, Westerterp-Plantenga MS
Effects of sleep fragmentation in healthy men on energy expenditure, substrate oxidation, physical activity, and exhaustion measured over 48 h in a respiratory chamber
Am J Clin Nutr. 2011 Sep;94(3):804-8. doi: 10.3945/ ajcn.111.017632. Epub 2011 Jul 27.
PMID: 21795436

 

Wijers SL, Schrauwen P, van Baak MA, Saris WH, van Marken Lichtenbelt WD.
Beta-adrenergic receptor blockade does not inhibit cold-induced thermogenesis in humans: possible involvement of brown adipose tissue.
J Clin Endocrinol Metab. 2011 Apr;96(4):E598-605. doi: 10.1210/jc.2010-1957. Epub 2011 Jan 26.
PMID:21270329

 

Veldhorst MA, Westerterp KR, van Vught AJ, Westerterp-Plantenga MS
Presence or absence of carbohydrates and the proportion of fat in a high-protein diet affect appetite suppression but not energy expenditure in normal-weight human subjects fed in energy balance
Br J Nutr. 2010 Nov;104(9):1395-405. doi: 10.1017/S0007114510002060. Epub 2010 Jun 22.
PMID: 20565999

 

Hoeks J, van Herpen NA, Mensink M, Moonen-Kornips E, van Beurden D, Hesselink MK, Schrauwen P
Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance
Diabetes. 2010 Sep;59(9):2117-25. doi: 10.2337/db10-0519. Epub 2010 Jun 23.
PMID: 20573749 | PMCID: PMC2927932

 

Wijers SL, Saris WH, van Marken Lichtenbelt WD.
Cold-induced adaptive thermogenesis in lean and obese.
Obesity (Silver Spring). 2010 Jun;18(6):1092-9. doi: 10.1038/oby.2010.74. Epub 2010 Apr 1.
PMID:20360754

 

Wijers SL, Smit E, Saris WH, Mariman EC, van Marken Lichtenbelt WD.
Cold- and overfeeding-induced changes in the human skeletal muscle proteome.
J Proteome Res. 2010 May 7;9(5):2226-35. doi: 10.1021/pr9010074.
PMID:20143783

 

Hochstenbach-Waelen A, Westerterp-Plantenga MS, Veldhorst MA, Westerterp KR
Single-protein casein and gelatin diets affect energy expenditure similarly but substrate balance and appetite differently in adults
J Nutr. 2009 Dec;139(12):2285-92. doi: 10.3945/jn.109.110403. Epub 2009 Oct 28.
PMID: 19864402

 

Oortwijn AW, Plasqui G, Reilly JJ, Okely AD
Feasibility of an activity protocol for young children in a whole room indirect calorimeter: a proof-of-concept study
J Phys Act Health. 2009 Sep;6(5):633-7.
PMID: 19953840

 

Veldhorst MA, Westerterp-Plantenga MS, Westerterp KR
Gluconeogenesis and energy expenditure after a high-protein, carbohydrate-free diet
Am J Clin Nutr. 2009 Sep;90(3):519-26. doi: 10.3945/ajcn.2009.27834. Epub 2009 Jul 29.
PMID: 19640952

 

Westerterp-Plantenga MS, Lejeune MP, Smeets AJ, Luscombe-Marsh ND
Sex differences in energy homeostatis following a diet relatively high in protein exchanged with carbohydrate, assessed in a respiration chamber in humans
Physiol Behav. 2009 Jun 22;97(3-4):414-9. doi: 10.1016/j. physbeh.2009.03.010. Epub 2009 Mar 21.
PMID: 19318111

 

van Hees VT, van Lummel RC, Westerterp KR
Estimating activity-related energy expenditure under sedentary conditions using a tri-axial seismic accelerometer
Obesity (Silver Spring). 2009 Jun;17(6):1287-92. doi: 10.1038/oby.2009.55. Epub 2009 Mar 12.
PMID: 19282829

 

Smeets AJ, Lejeune MP, Westerterp-Plantenga MS
Effects of oral fat perception by modified sham feeding on energy expenditure, hormones and appetite profile in the postprandial state
Br J Nutr. 2009 May;101(9):1360-8. doi: 10.1017/S0007114508079592. Epub 2008 Sep 25.
PMID: 18814804

 

van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM, Drossaerts JM, Kemerink GJ, Bouvy ND, Schrauwen P, Teule GJ.
Cold-activated brown adipose tissue in healthy men.
N Engl J Med. 2009 Apr 9;360(15):1500-8. doi: 10.1056/NEJMoa0808718. Erratum in: N Engl J Med. 2009 Apr 30;360(18):1917.
PMID:19357405

 

Hochstenbach-Waelen A, Veldhorst MA, Nieuwenhuizen AG, Westerterp-Plantenga MS, Westerterp KR
Comparison of 2 diets with either 25% or 10% of energy as casein on energy expenditure, substrate balance, and appetite profile
Am J Clin Nutr. 2009 Mar;89(3):831-8. doi:  0.3945/ajcn.2008.26917. Epub 2009 Jan 28.
PMID: 19176726

 

Smeets AJ, Westerterp-Plantenga MS
Acute effects on metabolism and appetite profile of one meal difference in the lower range of meal frequency
Br J Nutr.2008 Jun;99(6):1316-21. Epub 2007 Dec 6.
PMID: 18053311

 

Wijers SL, Schrauwen P, Saris WH, van Marken Lichtenbelt WD
Human skeletal muscle mitochondrial uncoupling is associated with cold induced adaptive thermogenesis
PLoS One. 2008 Mar 12;3(3):e1777. doi:10.1371/journal.pone.0001777.
PMID: 18335051 | PMCID: PMC2258415

 

Schoffelen PF, Westerterp KR
Intra-individual variability and adaptation of overnight- and sleeping metabolic rate
Physiol Behav. 2008 May 23;94(2):158-63. doi: 10.1016/j.physbeh.2007.12.013. Epub 2007 Dec 23.
PMID: 18234245

 

Westerterp KR
Physical activity as determinant of daily energy expenditure
Physiol Behav. 2008 Mar 18;93(4-5):1039-43. doi: 10.1016/j. physbeh.2008.01.021.Epub 2008 Jan 31. Review.
PMID: 18308349

 

Joosen AM, Bakker AH, Kersten S, Westerterp KR
The PPARgamma ligand rosiglitazone influences triacylglycerol metabolism in non-obese males,without increasing the transcriptional activity of PPARgamma in the subcutaneous adipose tissue
Br J Nutr. 2008 Mar;99(3):487-93. doi: 10.1017/ S0007114507824081. Epub 2008 Jan 4.
PMID: 18177513

 

Westerterp KR, Smeets A, Lejeune MP, Wouters-Adriaens MP, Westerterp-Plantenga MS
Dietary fat oxidation as a function of body fat
Am J Clin Nutr. 2008 Jan;87(1):132-5.
PMID: 18175746

 

Wijers SL, Saris WH, van Marken Lichtenbelt WD.
Individual thermogenic responses to mild cold and overfeeding are closely related.
J Clin Endocrinol Metab. 2007 Nov;92(11):4299-305. Epub 2007 Sep 4.
PMID:17785356

 

Kovacs EM, Westerterp-Plantenga MS
Effects of (-)-hydroxycitrate on net fat synthesis as de novo lipogenesis
Physiol Behav. 2006 Jul 30;88(4-5):371-81. Epub 2006 May 24.
PMID: 16725163

 

Wouters-Adriaens MP, Westerterp KR
Basal metabolic rate as a proxy for overnight energy expenditure: the effect of age
Br J Nutr. 2006 Jun;95(6):1166-70.
PMID: 16768840

 

Joosen AM, Bakker AH, Gering MJ, Westerterp KR
The effect of the PPARgamma ligand rosiglitazone on energy balance regulation
Diabetes Metab Res Rev. 2006 May-Jun;22(3):204-10.
PMID: 16110522

 

Lejeune MP, Westerterp KR, Adam TC, Luscombe-Marsh ND, Westerterp-Plantenga MS
Ghrelin and glucagon-like peptide 1 concentrations, 24-h satiety, and energy and substrate metabolism during a high-protein diet and measured in a respiration chamber
Am J Clin Nutr. 2006 Jan;83(1):89-94.
PMID: 16400055

 

Joosen AM, Gielen M, Vlietinck R, Westerterp KR
Genetic analysis of physical activity in twins
Am J Clin Nutr. 2005 Dec;82(6):1253-9.
PMID:16332658

 

Westerterp KR, Plasqui G, Goris AH
Water loss as a function of energy intake, physical activity and season
Br J Nutr. 2005 Feb;93(2):199-203.
PMID: 15788113

 

Westerterp-Plantenga MS
Fat intake and energy-balance effects
Physiol Behav. 2004 Dec 30;83(4):579-85. Review.
PMID: 15621063

 

van Ooijen AM, van Marken Lichtenbelt WD, van Steenhoven AA, Westerterp KR.
Seasonal changes in metabolic and temperature responses to cold air in humans.
Physiol Behav. 2004 Sep 15;82(2-3):545-53.
PMID:15276821

 

Saris WH, Schrauwen P
Substrate oxidation differences between high- and low-intensity exercise are compensated over 24 hours in obese men
Int J Obes Relat Metab Disord. 2004 Jun;28(6):759-65.
PMID: 15052277

 

Plasqui G, Westerterp KR
Seasonal variation in total energy expenditure and physical activity in Dutch young adults
Obes Res. 2004 Apr;12(4):688-94.
PMID: 15090638

 

Plasqui G, Kester AD, Westerterp KR
Seasonal variation in sleeping metabolic rate, thyroid activity, and leptin
Am J Physiol Endocrinol Metab. 2003 Aug;285(2):E338-43.
PMID: 12857676

 

Westerterp KR, Kester AD
Physical activity in confined conditions as an indicator of free-living physical activity
Obes Res. 2003 Jul;11(7):865-8.
PMID: 12855756

 

Kovacs EM, Lejeune MP, Westerterp-Plantenga MS
The effects of enterostatin intake on food intake and energy expenditure
Br J Nutr. 2003 Jul;90(1):207- 14.
PMID: 12844393

 

Kamphuis MM, Mela DJ, Westerterp-Plantenga MS
Diacylglycerols affect substrate oxidation and appetite in humans
Am J Clin Nutr. 2003 May;77(5):1133-9.
PMID: 12716663

 

Schrauwen P, Hinderling V, Hesselink MK, Schaart G, Kornips E, Saris WH, Westerterp-Plantenga M, Langhans W
Etomoxir-induced increase in UCP3 supports a role of uncoupling protein 3 as a mitochondrial fatty acid anion exporter
FASEB J. 2002 Oct;16(12):1688-90. Epub 2002 Aug 21.
PMID: 12206997

 

van Marken Lichtenbelt WD, Schrauwen P, van De Kerckhove S, Westerterp-Plantenga MS.
Individual variation in body temperature and energy expenditure in response to mild cold.
Am J Physiol Endocrinol Metab. 2002 May;282(5):E1077-83.
PMID:11934673

 

Westerterp-Plantenga MS, van Marken Lichtenbelt WD, Strobbe H, Schrauwen P.
Energy metabolism in humans at a lowered ambient temperature.
Eur J Clin Nutr. 2002 Apr;56(4):288-96.
PMID:11965504

 

Schrauwen P, Westerterp-Plantenga MS, Kornips E, Schaart G, van Marken Lichtenbelt WD.
The effect of mild cold exposure on UCP3 mRNA expression and UCP3 protein content in humans.
Int J Obes Relat Metab Disord. 2002 Apr;26(4):450-7.
PMID:12075570

 

Westerterp-Plantenga MS, van Marken Lichtenbelt WD, Cilissen C, Top S.
Energy metabolism in women during short exposure to the thermoneutral zone.
Physiol Behav. 2002 Feb 1-15;75(1-2):227-35.
PMID:11890972

 

Westerterp-Plantenga MS, Saris WH, Hukshorn CJ, Campfield LA
Effects of weekly administration of pegylated recombinant human OB protein on appetite profile and energy metabolism in obese men
Am J Clin Nutr. 2001 Oct;74(4):426-34.
PMID: 11566639

 

Kovacs EM, Westerterp-Plantenga MS, Saris WH
The effects of 2-week ingestion of (–)-hydroxycitrate and (–)-hydroxycitrate combined with mediumchain triglycerides on satiety, fat oxidation, energy expenditure and body weight
Int J Obes Relat Metab Disord. 2001 Jul;25(7):1087-94.
PMID: 11443511

 

van Marken Lichtenbelt WD, Westerterp-Plantenga MS, van Hoydonck P.
Individual variation in the relation between body temperature and energy expenditure in response to elevated ambient temperature.
Physiol Behav. 2001 May;73(1-2):235-42.
PMID:11399317

 

Westerterp KR
Pattern and intensity of physical activity
Nature. 2001 Mar29;410(6828):539.
PMID:11279482

 

Schrauwen P, van Marken Lichtenbelt WD, Westerterp KR.
Fat and carbohydrate balances during adaptation to a high-fat diet.
Am J Clin Nutr. 2000 Nov;72(5):1239-41. No abstract available.
PMID:11063462

 

van Gemert WG, Westerterp KR, van Acker BA, Wagenmakers AJ, Halliday D, Greve JM, Soeters PB
Energy, substrate and protein metabolism in morbid obesity before, during and after massive weight loss
Int J Obes Relat Metab Disord. 2000 Jun;24(6):711-8.
PMID: 10878677

 

Schrauwen P, Wagenmakers AJ, van Marken Lichtenbelt WD, Saris WH, Westerterp KR.
Increase in fat oxidation on a high-fat diet is accompanied by an increase in triglyceride-derived fatty acid oxidation.
Diabetes. 2000 Apr;49(4):640-6.
PMID:10871203

 

van Mil EA, Westerterp KR, Gerver WJ, Curfs LM, Schrander-Stumpel CT, Kester AD, Saris WH
Energy expenditure at rest and during sleep in children with Prader-Willi syndrome is explained by body composition
Am J Clin Nutr. 2000 Mar;71(3):752-6.
PMID: 10702169

 

Gerver WJ, De Bruin R, Delemarre v d Waal HA, Aldewereld B, Theunissen P, Westerterp KR
Effects of discontinuation of growth hormone treatment on body composition and metabolism
Horm Res. 2000;53(5):215-20.
PMID: 11150882

 

Pasman WJ, Westerterp MS, Saris WH
The effect of body weight changes and endurance training on 24h substrate oxidation
Int J Obes Relat Metab Disord. 1999 Dec;23(12):1223-32.
PMID: 10643677

 

Westerterp-Plantenga MS, Rolland V, Wilson SA, Westerterp KR
Satiety related to 24 h diet-induced thermogenesis during high protein/carbohydrate vs high fat diets measured in a respiration chamber
Eur J Clin Nutr. 1999 Jun;53(6):495-502.
PMID: 10403587

 

Westerterp KR, Wilson SA, Rolland V
Diet induced thermogenesis measured over 24h in a respiration chamber: effect of diet composition
Int J Obes Relat Metab Disord. 1999 Mar;23(3):287-92.
PMID: 10193874

 

Schrauwen P, Xia J, Bogardus C, Pratley RE, Ravussin E
Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians
Diabetes. 1999 Jan;48(1):146-9.
PMID: 9892236

 

Schrauwen P, Lichtenbelt WD, Saris WH, Westerterp KR
Fat balance in obese subjects: role of glycogen stores
Am J Physiol. 1998 Jun;274(6 Pt 1):E1027- 33.
PMID: 9611152

 

Brouns F, Saris WH, Stroecken J, Beckers E, Thijssen R, Rehrer NJ, ten Hoor F
Eating, drinking, and cycling. A controlled Tour de France simulation study, Part I
Int J Sports Med. 1989 May;10 Suppl 1:S32-40. Review.
PMID: 2663741

 

Brouns F, Saris WH, Stroecken J, Beckers E, Thijssen R, Rehrer NJ, ten Hoor F
Eating, drinking, and cycling. A controlled Tour de France simulation study, Part II. Effect of diet manipulation
Int J Sports Med. 1989 May;10 Suppl 1:S41-8. Review.
PMID: 2663742

 

Brouns F, Saris WH, Beckers E, Adlercreutz H, van der Vusse GJ, Keizer HA, Kuipers H, Menheere P, Wagenmakers AJ, ten Hoor F
Metabolic changes induced by sustained exhaustive cycling and diet manipulation
Int J Sports Med. 1989 May;10 Suppl 1:S49-62. Review.
PMID: 2663743

 

van Gemert WG, Westerterp KR, Greve JW, Soeters PB
Reduction of sleeping metabolic rate after vertical banded gastroplasty
Int J Obes Relat Metab Disord. 1998 Apr;22(4):343-8.
PMID: 9578240

 

van Marken Lichtenbelt WD, Heidendal GA, Westerterp KR
Energy expenditure and physical activity in relation to bone mineral density in women with anorexia nervosa
Eur J Clin Nutr. 1997 Dec;51(12):826-30.
PMID: 9426357

 

Westerterp KR, Bouten CV
Physical activity assessment: comparison between movement registration and doubly labeled water method
Z Ernahrungswiss. 1997 Dec;36(4):263-7.
PMID: 9467213

 

Schrauwen P, van Marken Lichtenbelt WD, Saris WH, Westerterp KR.
The adaptation of nutrient oxidation to nutrient intake on a high-fat diet.
Z Ernahrungswiss. 1997 Dec;36(4):306-9.
PMID:9467222

 

Paul F. M. Schoffelen, Klaas R. Westerterp, Wim H. M. Saris, and Foppe Ten Hoor
A dual-respiration chamber system with automated calibration.
Journal of Applied Physiology. 1997 Dec;83(6):2064-72.
PMID: 9390982

 

van Marken Lichtenbelt WD, Mensink RP, Westerterp KR.
The effect of fat composition of the diet on energy metabolism.
Z Ernahrungswiss. 1997 Dec;36(4):303-5.
PMID:9467221

 

Schrauwen P, van Marken Lichtenbelt WD, Westerterp KR.
Energy balance in a respiration chamber: individual adjustment of energy intake to energy expenditure.
Int J Obes Relat Metab Disord. 1997 Sep;21(9):769-74.
PMID:9376889

 

Schrauwen P, van Marken Lichtenbelt WD, Saris WH, Westerterp KR
Role of glycogen-lowering exercise in the change of fat oxidation in response to a high-fat diet
Am J Physiol. 1997 Sep;273(3 Pt 1):E623-9.
PMID: 9316454

 

Schrauwen P, van Marken Lichtenbelt WD, Saris WH, Westerterp KR.
Changes in fat oxidation in response to a high-fat diet.
Am J Clin Nutr. 1997 Aug;66(2):276-82.
PMID:9250105

 

Schrauwen P, van Marken Lichtenbelt WD, Westerterp KR, Saris WH.
Effect of diet composition on leptin concentration in lean subjects.
Metabolism. 1997 Apr;46(4):420-4.
PMID:9109847

 

Bouten CV, Verboeket-van de Venne WP, Westerterp KR, Verduin M, Janssen JD
Daily physical activity assessment: comparison between movement registration and doubly labeled water
J Appl Physiol (1985). 1996 Aug;81(2):1019-26.
PMID: 8872675

 

Verboeket-van de Venne WP, Westerterp KR, Hermans-Limpens TJ, de Graaf C, van het Hof KH, Weststrate JA
Long-term effects of consumption of full-fat or reduced-fat products in healthy non-obese volunteers: assessment of energy expenditure and substrate oxidation
Metabolism. 1996 Aug;45(8):1004- 10.
PMID: 8769360

 

Yerboeket-van de Venne WP, Westerterp KR
Effects of dietary fat and carbohydrate exchange on human energy metabolism
Appetite. 1996 Jun;26(3):287-300.
PMID: 8800484

 

van den Berg-Emons HJ, Saris WH, de Barbanson DC, Westerterp KR, Huson A, van Baak MA
Daily physical activity of schoolchildren with spastic diplegia and of healthy control subjects
J Pediatr. 1995 Oct;127(4):578-84.
PMID: 7562279.

 

Pannemans DL, Bouten CV, Westerterp KR
24 h energy expenditure during a standardized activity protocol in young and elderly men
Eur J Clin Nutr. 1995 Jan;49(1):49-56.
PMID: 7713051

 

Verboeket-van de Venne WP, Westerterp KR, van Hoek B, Swart GR
Energy expenditure and substrate metabolism in patients with cirrhosis of the liver: effects of the pattern of food intake
Gut. 1995 Jan;36(1):110-6.
PMID: 7890212 | PMCID: PMC1382363

 

Verboeket-van de Venne WP, Westerterp KR, ten Hoor F
Substrate utilization in man: effects of dietary fat and carbohydrate
Metabolism. 1994 Feb;43(2):152-6.
PMID: 8121294

 

Westerterp KR, Meijer GA, Schoffelen P, Janssen EM
Body mass, body composition and sleeping metabolic rate before, during and after endurance training
Eur J Appl Physiol Occup Physiol. 1994;69(3):203-8.
PMID: 8001530

 

Verboeket-van de Venne WP, Westerterp KR, Kester AD
Effect of the pattern of food intake on human energy metabolism
Br J Nutr. 1993 Jul;70(1):103-15.
PMID: 8399092

 

Verboeket-van de Venne WP, Westerterp KR
Frequency of feeding, weight reduction and energy metabolism
Int J Obes Relat Metab Disord. 1993 Jan;17(1):31-6.
PMID: 8383639

 

Westerterp KR, Meijer GA, Janssen EM, Saris WH, Ten Hoor F
Long-term effect of physical activity on energy balance and body composition
Br J Nutr. 1992 Jul;68(1):21-30
PMID: 1390606

 

Meijer GA, Westerterp KR, van Hulsel AM, ten Hoor F
Physical activity and energy expenditure in lean and obese adult human subjects
Eur J Appl Physiol Occup Physiol. 1992;65(6):525-8.
PMID: 1483440

 

Westerterp KR, Saris WH, Soeters PB, ten Hoor F
Determinants of weight loss after vertical banded gastroplasty
Int J Obes. 1991 Aug;15(8):529-34.
PMID: 1938096

 

Verboeket-van de Venne WP, Westerterp KR
Influence of the feeding frequency on nutrient utilization in man: consequences for energy metabolism
Eur J Clin Nutr. 1991 Mar;45(3):161-9.
PMID: 1905998

 

Westerterp KR, Meijer GA, Saris WH, Soeters PB, Winants Y, ten Hoor F
Physical activity and sleeping metabolic rate
Med Sci Sports Exerc. 1991 Feb;23(2):166-70.
PMID: 2017012

 

Meijer GA, Westerterp KR, Seyts GH, Janssen GM, Saris WH, ten Hoor F
Body composition and sleeping metabolic rate in response to a 5-month endurance-training programme in adults
Eur J Appl Physiol Occup Physiol. 1991;62(1):18-21.
PMID: 2007390

 

Webb P, Saris WH, Schoffelen PF, Van Ingen Schenau GJ, Ten Hoor F
The work of walking: a calorimetric study
Med Sci Sports Exerc. 1988 Aug;20(4):331-7.
PMID: 3173041

 

Van Dale D, Saris WH, Schoffelen PF, Ten Hoor F
Does exercise give an additional effect in weight reduction regimens?
Int J Obes. 1987;11(4):367-75.
PMID: 3667068